Ancient thread I know, but what the heck.
Matty, I just had the same problem. You need to set only the OSS driver to be used in winecfg, then open up the GNOME mixer, change driver to OSS (File menu), then go to record tab and turn on record control for PCM. Funny how things in Linux work the same exact way as in Windows.
Edit: dude, what kinda video card do you have that lets you run R4 and Compiz/Beryl at the same time?

my (wimpy, pathetic little) Geforce FX5200 couldn't dream of doing that.
--Dan